Biohacking Guide peptide vault logoBioHackingGuide
    CommunityBHGUIDE Quick Link
    r/BioHackingGuideShop Peptides

    Nootropics & Cognitive Enhancement

    Research hub for cognitive peptides, brain health compounds, and performance nootropics

    Browse by Category

    Explore cognitive research compounds organized by primary mechanism

    🎯

    Dopamine & Motivation

    Compounds that support dopaminergic signaling and motivation pathways

    🧠

    Focus & Attention

    Research peptides for sustained focus and executive function

    📚

    Memory & Learning

    Compounds studied for memory consolidation and neuroplasticity

    🧘

    Anxiety & Stress

    Anxiolytic peptides for stress resilience without sedation

    😴

    Sleep & Recovery

    Compounds that improve sleep architecture and overnight recovery

    🧬

    BDNF & Neuroplasticity

    Peptides that upregulate BDNF and promote neuronal growth

    Featured Nootropic Compounds

    Research profiles for the most studied cognitive peptides and compounds

    Semax

    BDNF & Neuroplasticity

    ACTH-derived peptide studied for BDNF upregulation, dopaminergic modulation, and cognitive enhancement.

    View Profile

    Selank

    Anxiety & Stress

    Tuftsin analogue with anxiolytic and nootropic properties; studied for stress resilience without sedation.

    View Profile

    Dihexa

    Memory & Learning

    Potent neuroplasticity compound studied for synaptogenesis and memory consolidation in preclinical models.

    View Profile

    NA-Semax

    Focus & Attention

    N-acetylated form of Semax with enhanced stability and CNS penetration for cognitive support.

    View Profile

    NA-Selank

    Anxiety & Stress

    N-acetylated Selank variant with prolonged anxiolytic action and improved bioavailability.

    View Profile

    Methylene Blue

    Focus & Attention

    Mitochondrial electron carrier studied for neuroprotection, memory enhancement, and cognitive resilience.

    View Profile

    DSIP

    Sleep & Recovery

    Delta sleep-inducing peptide studied for slow-wave sleep architecture and GH pulse optimization.

    View Profile

    PE-22-28

    Dopamine & Motivation

    Spadin analogue and TREK-1 blocker studied for rapid antidepressant-like effects and neuroplasticity.

    View Profile

    P-21

    BDNF & Neuroplasticity

    CNTF-derived peptide studied for neurogenesis, BDNF upregulation, and cognitive performance in rodent models.

    View Profile

    Noopept

    Memory & Learning

    Dipeptide nootropic studied for memory consolidation, BDNF expression, and neuroprotection.

    View Profile

    Nootropic Stack Guides

    In-depth guides for building and running cognitive research protocols

    🧠

    Cognitive Enhancement: Semax + Selank

    A practical guide to the most studied cognitive peptide stack — mechanisms, dosing, and protocol structure.

    Read Guide
    😴

    Deep Sleep & BDNF Protocol

    How slow-wave sleep drives BDNF production, and which compounds support optimal sleep architecture.

    Read Guide
    🎯

    Dopamine Reset Protocol

    A structured 7-day protocol for restoring motivational baseline and dopamine receptor sensitivity.

    Read Guide

    Research purposes only. All compounds listed are for research purposes only. Not medical advice. Consult a qualified healthcare professional before beginning any research protocol.

    Biohacking Guide peptide vault logoBioHackingGuide

    Your peptide guide for research, dosing, and biohacking education.

    Quick Links

    Peptide Dosage CalculatorPeptide Guide TableTrusted Peptide SourcesPeptide Guides

    Community

    Biohacking Communityr/BioHackingGuide Optimum Formula

    Stay Updated

    Sign up & get our free Master Peptide Guide PDF — doses, cycles, stacks & red flags for 51 compounds.

    Disclaimer: All information on this site is for educational and research purposes only. Peptides and research chemicals are not intended for human consumption. They are sold strictly for in-vitro research, laboratory use, or as reference standards. Always consult with qualified professionals before any research activities.

    © 2026 BioHackingGuide. All rights reserved.

    Age Verification

    This site contains research and educational content intended for adults. You must be 21 or older to continue.